Markers on the Genetic Chromosome
Heritable traits that can be assayed (markers) are of many different kinds:
- Visible (physical appearance): height, shape, color, growth rate, etc.
- Auxotrophic (growth requirements). For microorganisms such as baker's yeast, though some markers are visual markers affecting colony color or morphology, many are auxotrophic markers. Search here for terms such as 3-letter amino acid abbreviations for loci whose mutation causes a requirement for that amino acid for growth.
- Antibiotic sensitivities and resistances.
- Conditional: nutrition (auxotrophy); temperature ( ts mutants); light; developmental; etc.
Characteristics of several biomolecules can serve as markers on the genetic chromosome.
- RFLP's (restriction fragment length polymorphisms)
- RAPD's (random amplified polymorphic DNA)
- AFLP's (amplified fragment length polymorphisms)
- Microsatellite repeats--VNTR's
- SSCP's (single strand conformation polymorphism)
- SNP's (single nucleotide polymorphism)
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This is page 1112 of Molecular Genetics by Ulrich Melcher, ©1997, 1998, 1999
E-mail inquiries to U. Melcher------------Last Updated: 8 September, 2003